2-{3-[3-chloro-5-(cyclopropylmethoxy)phenyl]-2-oxo[2H-[1,3'-bipyridine]]-5-yl}benzonitrile
P0DTD1 — Replicase polyprotein 1ab
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand XFD
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand XFD
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P0DTD1 | n/a | 7l14 | XFD | A | 400 | e7l14A1 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |
| P0DTD1 | n/a | 7l14 | XFD | A | 400 | e7l14A2 | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Peptidase_C30 |
| P0DTD1 | n/a | 7l14 | XFD | B | 400 | e7l14B1 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |
| P0DTD1 | n/a | 7l14 | XFD | B | 400 | e7l14B2 | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Peptidase_C30 |