4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-[(4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamide
P10415 — Apoptosis regulator Bcl-2
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB12340
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand DB12340
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P10415 | DB12340 | 4lvt | 1XJ | A | 301 | e4lvtA1 | Toxins' membrane translocation domains | Bcl-2 inhibitors of programmed cell death | Bcl-2 inhibitors of programmed cell death | Bcl-2,BH4 |
| P10415 | DB12340 | 4lvt | 1XJ | B | 301 | e4lvtB1 | Toxins' membrane translocation domains | Bcl-2 inhibitors of programmed cell death | Bcl-2 inhibitors of programmed cell death | Bcl-2,BH4 |
| P10415 | DB12340 | 6qgh | 1XJ | A | 401 | e6qghA1 | Toxins' membrane translocation domains | Bcl-2 inhibitors of programmed cell death | Bcl-2 inhibitors of programmed cell death | Bcl-2,BH4 |