4-[4-({4'-chloro-3-[2-(dimethylamino)ethoxy]biphenyl-2-yl}methyl)piperazin-1-yl]-2-(1H-indol-5-yloxy)-N-({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}sulfonyl)benzamide
P10415 — Apoptosis regulator Bcl-2
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand 1Y1
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand 1Y1
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P10415 | n/a | 4man | 1Y1 | A | 301 | e4manA1 | Toxins' membrane translocation domains | Bcl-2 inhibitors of programmed cell death | Bcl-2 inhibitors of programmed cell death | Bcl-2,BH4 |
| P10415 | n/a | 4man | 1Y1 | B | 301 | e4manB1 | Toxins' membrane translocation domains | Bcl-2 inhibitors of programmed cell death | Bcl-2 inhibitors of programmed cell death | Bcl-2,BH4 |