N,N-dibutyl-4-chloranyl-1-[2-(3,4-dihydro-1H-isoquinolin-2-ylcarbonyl)-4-[(7-iodanylnaphthalen-2-yl)sulfonylcarbamoyl]phenyl]-5-methyl-pyrazole-3-carboxamide

P10415 — Apoptosis regulator Bcl-2

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 398

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 398

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P10415	n/a	4aq3	398	A	1163	e4aq3A2	Toxins' membrane translocation domains	Bcl-2 inhibitors of programmed cell death	Bcl-2 inhibitors of programmed cell death	Bcl-2,BH4
P10415	n/a	4aq3	398	A	1163	e4aq3C2	Toxins' membrane translocation domains	Bcl-2 inhibitors of programmed cell death	Bcl-2 inhibitors of programmed cell death	Bcl-2,BH4
P10415	n/a	4aq3	398	A	1163	e4aq3E2	Toxins' membrane translocation domains	Bcl-2 inhibitors of programmed cell death	Bcl-2 inhibitors of programmed cell death	Bcl-2,BH4
P10415	n/a	4aq3	398	B	1163	e4aq3B2	Toxins' membrane translocation domains	Bcl-2 inhibitors of programmed cell death	Bcl-2 inhibitors of programmed cell death	Bcl-2,BH4
P10415	n/a	4aq3	398	B	1163	e4aq3D2	Toxins' membrane translocation domains	Bcl-2 inhibitors of programmed cell death	Bcl-2 inhibitors of programmed cell death	Bcl-2,BH4
P10415	n/a	4aq3	398	C	1163	e4aq3C2	Toxins' membrane translocation domains	Bcl-2 inhibitors of programmed cell death	Bcl-2 inhibitors of programmed cell death	Bcl-2,BH4
P10415	n/a	4aq3	398	D	1163	e4aq3B2	Toxins' membrane translocation domains	Bcl-2 inhibitors of programmed cell death	Bcl-2 inhibitors of programmed cell death	Bcl-2,BH4
P10415	n/a	4aq3	398	D	1163	e4aq3D2	Toxins' membrane translocation domains	Bcl-2 inhibitors of programmed cell death	Bcl-2 inhibitors of programmed cell death	Bcl-2,BH4
P10415	n/a	4aq3	398	E	1163	e4aq3A2	Toxins' membrane translocation domains	Bcl-2 inhibitors of programmed cell death	Bcl-2 inhibitors of programmed cell death	Bcl-2,BH4
P10415	n/a	4aq3	398	E	1163	e4aq3E2	Toxins' membrane translocation domains	Bcl-2 inhibitors of programmed cell death	Bcl-2 inhibitors of programmed cell death	Bcl-2,BH4
P10415	n/a	4aq3	398	E	1163	e4aq3F2	Toxins' membrane translocation domains	Bcl-2 inhibitors of programmed cell death	Bcl-2 inhibitors of programmed cell death	Bcl-2,BH4
P10415	n/a	4aq3	398	F	1163	e4aq3F2	Toxins' membrane translocation domains	Bcl-2 inhibitors of programmed cell death	Bcl-2 inhibitors of programmed cell death	Bcl-2,BH4