DrugDomain logoDrugDomain

1-[2-[[(3~{S})-3-(aminomethyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]carbonyl]phenyl]-~{N},~{N}-dibutyl-5-methyl-pyrazole-3-carboxamide

P10415 — Apoptosis regulator Bcl-2

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand J1Q

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand J1Q

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P10415n/a6qgkJ1QA401e6qgkA1Toxins' membrane translocation domainsBcl-2 inhibitors of programmed cell deathBcl-2 inhibitors of programmed cell deathBcl-2,BH4