Phosphoric acid mono-[5-(5-{4-[2-(4-chloro-phenyl)-4,4-dimethyl-cyclohex-1-enylmethyl]-piperazin-1-yl}-2-{3-nitro-4-[(tetrahydro-pyran-4-ylmethyl)-amino]-benzenesulfonylaminocarbonyl}-phenoxy)-pyrrolo[2,3-b]pyridin-7-ylmethyl] ester
P10415 — Apoptosis regulator Bcl-2
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand XZD
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand XZD
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P10415 | n/a | 7lhb | XZD | A | 4000 | e7lhbA1 | Toxins' membrane translocation domains | Bcl-2 inhibitors of programmed cell death | Bcl-2 inhibitors of programmed cell death | Bcl-2,BH4 |
| P10415 | n/a | 7lhb | XZD | A | 4000 | e7lhbB1 | Toxins' membrane translocation domains | Bcl-2 inhibitors of programmed cell death | Bcl-2 inhibitors of programmed cell death | Bcl-2,BH4 |
| P10415 | n/a | 7lhb | XZD | B | 4000 | e7lhbB1 | Toxins' membrane translocation domains | Bcl-2 inhibitors of programmed cell death | Bcl-2 inhibitors of programmed cell death | Bcl-2,BH4 |
| P10415 | n/a | 7lhb | XZD | C | 4000 | e7lhbC1 | Toxins' membrane translocation domains | Bcl-2 inhibitors of programmed cell death | Bcl-2 inhibitors of programmed cell death | Bcl-2,BH4 |