Attributes
UniProt ID
Protein Name
Mast/stem cell growth factor receptor Kit
Ligand Name
Avapritinib
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
DWYRIWUZIJHQKQ-SANMLTNESA-N
SMILES
CC(c1ccc(cc1)F)(c2cnc(nc2)N3CCN(CC3)c4c5cc(cn5ncn4)c6cnn(c6)C)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: P10721_F1
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Color Legend
Unassigned regionsLigand / hetero atomsnD6
ECOD domains from AlphaFold model interacting with ligand DB15233
| UniProt | DrugBank | PDB Ligand | ECOD Domain | Range Definition |
|---|---|---|---|---|
| P10721 | DB15233 | 9JI | nD6 | 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700, 751-950, 556-700,751-950 |