PYRUVIC ACID

P11177 — Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB00119

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
P11177	DB00119	PYR	nD1	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transket_pyr

Show other predicted domains (78)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
1NI4	e1ni4B1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e1ni4D1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e1ni4B2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e1ni4D2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
2OZL	e2ozlB1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e2ozlD1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e2ozlB2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e2ozlD2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
3EXE	e3exeB1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exeD1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exeF1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exeH1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exeB2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exeD2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exeF2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exeH2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
3EXF	e3exfB1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exfD1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exfF1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exfH1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exfB2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exfD2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exfF2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exfH2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
3EXG	e3exgB1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exgD1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exgF1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exgH1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exgJ1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exgL1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exgN1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exgP1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exgR1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exgT1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exgV1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exgX1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exgZ1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exg21	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exg41	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exg61	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exgB2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exgD2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exgF2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exgH2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exgJ2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exgL2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exgN2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exgP2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exgR2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exgT2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exgV2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exgX2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exgZ2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exg22	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exg42	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exg62	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
3EXH	e3exhB1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exhD1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exhF1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exhH1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e3exhB2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exhD2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exhF2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e3exhH2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
3EXI	e3exiB1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
3EXI	e3exiB2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
6CER	e6cerD2	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e6cerB1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e6cerF2	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e6cerH1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e6cerD1	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e6cerB2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e6cerF1	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e6cerH2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
6CFO	e6cfoB1	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e6cfoD2	7522.1.1	TK C-terminal domain-like	TK C-terminal domain-like	TK C-terminal domain-like	Transketolase_C
	e6cfoB2	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N
	e6cfoD1	7574.1.1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Transketolase_N

ECOD domains from experimental PDB structures interacting with ligand DB00119

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found