DrugDomain logoDrugDomain

Attributes

UniProt ID
P11177
Protein Name
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
Ligand Name
THIAMINE DIPHOSPHATE
DrugBank ID
None
PDB Ligand Accession
TPP
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
AYEKOFBPNLCAJY-UHFFFAOYSA-O
SMILES
Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCOP(=O)(O)OP(=O)(O)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 1NI4
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Color Legend
Unassigned regionsLigand / hetero atomse1ni4A1e1ni4B1e1ni4B2e1ni4C1e1ni4D1e1ni4D2
ECOD domains from experimental PDB structures interacting with ligand TPP
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P11177n/aTPP1ni4e1ni4B2B:0-191
P11177n/aTPP1ni4e1ni4D2D:0-191
P11177n/aTPP2ozle2ozlB2B:0-191
P11177n/aTPP2ozle2ozlD2D:0-191
P11177n/aTPP3exee3exeB2B:1-191
P11177n/aTPP3exee3exeD2D:1-191
P11177n/aTPP3exee3exeF2F:1-191
P11177n/aTPP3exee3exeH2H:1-191
P11177n/aTPP3exfe3exfB2B:1-191
P11177n/aTPP3exfe3exfD2D:1-191
P11177n/aTPP3exfe3exfF2F:1-191
P11177n/aTPP3exfe3exfH2H:1-191
P11177n/aTPP3exhe3exhB2B:1-191
P11177n/aTPP3exhe3exhD2D:1-191
P11177n/aTPP3exhe3exhF2F:1-191
P11177n/aTPP3exhe3exhH2H:1-191
P11177n/aTPP6cere6cerB2B:0-191
P11177n/aTPP6cere6cerD1D:-1-191
P11177n/aTPP6cere6cerF1F:0-191
P11177n/aTPP6cere6cerH2H:-1-191