4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile

P11274 — Breakpoint cluster region protein

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB06616

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
P11274	DB06616	DB8	nD3	220.1.1	PH domain-like	PH domain-like	PH domain-like	SOS1_NGEF_PH
P11274	DB06616	DB8	nD5	11.2.1	Immunoglobulin-like beta-sandwich	C2 domain	C2 domain	C2
P11274	DB06616	DB8	nD6	189.1.1	GTPase activation domain, GAP	GTPase activation domain, GAP	GTPase activation domain, GAP	RhoGAP

Show other predicted domains (12)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
1K1F	e1k1fA1	534.1.1	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl_Oligo
	e1k1fF1	534.1.1	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl_Oligo
	e1k1fH1	534.1.1	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl_Oligo
	e1k1fE1	534.1.1	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl_Oligo
	e1k1fG1	534.1.1	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl_Oligo
	e1k1fB1	534.1.1	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl_Oligo
	e1k1fC1	534.1.1	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl_Oligo
	e1k1fD1	534.1.1	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl oncoprotein oligomerization domain	Bcr-Abl_Oligo
5N6R	e5n6rA1	133.1.1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
5N7E	e5n7eB1	133.1.1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
5OC7	e5oc7D1	220.1.1	PH domain-like	PH domain-like	PH domain-like	PH
5OC7	e5oc7A1	220.1.1	PH domain-like	PH domain-like	PH domain-like	PH

ECOD domains from experimental PDB structures interacting with ligand DB06616

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found