Attributes
UniProt ID
Protein Name
DNA topoisomerase 1
Ligand Name
(4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL 1,4'-BIPIPERIDINE-1'-CARBOXYLATE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
UWKQSNNFCGGAFS-XIFFEERXSA-N
SMILES
CCc1c2cc(ccc2nc3c1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: P11387_F1
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Color Legend
Unassigned regionsLigand / hetero atomsnD3nD5
ECOD domains from AlphaFold model interacting with ligand DB00762
| UniProt | DrugBank | PDB Ligand | ECOD Domain | Range Definition |
|---|---|---|---|---|
| P11387 | DB00762 | CP0 | nD3 | 436-585 |
| P11387 | DB00762 | CP0 | nD5 | 586-640, 711-765, 586-640, 711-765, 586-640, 711-765, 586-640, 711-765, 586-640, 711-765, 586-640, 711-765, 586-640, 711-765, 586-640, 711-765, 586-640, 711-765, 586-640, 711-765, 586-640, 711-765, 586-640, 711-765, 586-640, 711-765, 586-640, 711-765, 586-640,711-765 |