DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
DNA topoisomerase 1
Ligand Name
4-ETHYL-4-HYDROXY-1,12-DIHYDRO-4H-2-OXA-6,12A-DIAZA-DIBENZO[B,H]FLUORENE-3,13-DIONE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
VSJKWCGYPAHWDS-FQEVSTJZSA-N
SMILES
CCC1(C2=C(COC1=O)C(=O)N3Cc4cc5ccccc5nc4C3=C2)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 1T8I
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Color Legend
Unassigned regionsLigand / hetero atomse1t8iA1e1t8iA2e1t8iA4e1t8iA5e1t8iA6
ECOD domains from experimental PDB structures interacting with ligand DB04690
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P11387DB04690EHD1t8ie1t8iA1A:213-229,A:320-430
P11387DB04690EHD1t8ie1t8iA2A:431-583
P11387DB04690EHD1t8ie1t8iA6A:585-644,A:717-765