2,10-DIHYDROXY-12-(BETA-D-GLUCOPYRANOSYL)-6,7,12,13-TETRAHYDROINDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOLE-5,7-DIONE
P11387 — DNA topoisomerase 1
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand SA3
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand SA3
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P11387 | n/a | 1seu | SA3 | D | 990 | e1seuA1 | Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment | Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment | Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment | Topoisom_I_N |
| P11387 | n/a | 1seu | SA3 | D | 990 | e1seuA6 | HTH | HTH | DNA breaking-rejoining enzymes | Topoisom_I,Topo_C_assoc |