Attributes
UniProt ID
Protein Name
DNA topoisomerase 1
Ligand Name
(S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
UCFGDBYHRUNTLO-QHCPKHFHSA-N
SMILES
CCC1(C2=C(COC1=O)C(=O)N3Cc4cc5c(ccc(c5CN(C)C)O)nc4C3=C2)O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 1K4T
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Color Legend
Unassigned regionsLigand / hetero atomse1k4tA1e1k4tA2e1k4tA3e1k4tA4e1k4tA5
ECOD domains from experimental PDB structures interacting with ligand DB01030
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P11387 | DB01030 | TTC | 1k4t | e1k4tA1 | A:213-229,A:320-430 |
| P11387 | DB01030 | TTC | 1k4t | e1k4tA2 | A:431-584 |
| P11387 | DB01030 | TTC | 1k4t | e1k4tA3 | A:585-640,A:713-765 |
| P11387 | DB01030 | TTC | 1rr8 | e1rr8C5 | C:431-584 |
| P11387 | DB01030 | TTC | 1rr8 | e1rr8C6 | C:585-636,C:708-765 |
| P11387 | DB01030 | TTC | 1rr8 | e1rr8C8 | C:201-230,C:320-431 |
| P11387 | DB01030 | TTC | 1rrj | e1rrjA1 | A:213-229,A:320-430 |
| P11387 | DB01030 | TTC | 1rrj | e1rrjA2 | A:431-583 |
| P11387 | DB01030 | TTC | 1rrj | e1rrjA3 | A:584-635,A:713-764 |