2-(1-DIMETHYLAMINOMETHYL-2-HYDROXY-8-HYDROXYMETHYL-9-OXO-9,11-DIHYDRO-INDOLIZINO[1,2-B]QUINOLIN-7-YL)-2-HYDROXY-BUTYRIC ACID

P11387 — DNA topoisomerase 1

ECOD Domain Annotations

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P11387	n/a	1k4t	TTG	C	991	e1k4tA1	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Topoisom_I_N
P11387	n/a	1k4t	TTG	C	991	e1k4tA2	HTH	HTH	DNA breaking-rejoining enzymes	Topoisom_I
P11387	n/a	1k4t	TTG	C	991	e1k4tA3	HTH	HTH	DNA breaking-rejoining enzymes	Topoisom_I,Topo_C_assoc
P11387	n/a	1rr8	TTG	A	1991	e1rr8C5	HTH	HTH	DNA breaking-rejoining enzymes	Topoisom_I
P11387	n/a	1rr8	TTG	A	1991	e1rr8C6	HTH	HTH	DNA breaking-rejoining enzymes	Topo_C_assoc
P11387	n/a	1rr8	TTG	A	1991	e1rr8C8	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Topoisom_I_N
P11387	n/a	1rrj	TTG	B	991	e1rrjA1	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Topoisom_I_N
P11387	n/a	1rrj	TTG	B	991	e1rrjA2	HTH	HTH	DNA breaking-rejoining enzymes	Topoisom_I
P11387	n/a	1rrj	TTG	B	991	e1rrjA3	HTH	HTH	DNA breaking-rejoining enzymes	Topoisom_I,Topo_C_assoc