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N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide

P11388 — DNA topoisomerase 2-alpha

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Attributes

UniProt ID
P11388
Protein Name
DNA topoisomerase 2-alpha
Ligand Name
N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide
DrugBank ID
DB00276
PDB Ligand Accession
ASW
ChEMBL ID
CHEMBL43
PubChem ID
2179
InChIKey
XCPGHVQEEXUHNC-UHFFFAOYSA-N
SMILES
COc1cc(ccc1Nc2c3ccccc3nc4c2cccc4)NS(=O)(=O)C
Drug Action
inhibitor
Affinity Metrics
ic50:1000 nM
ec50:720 nM