N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide

P11388 — DNA topoisomerase 2-alpha

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB00276

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
P11388	DB00276	ASW	nD1	225.1.1	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HATPase_c
P11388	DB00276	ASW	nD2	212.1.1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	DNA_gyraseB
P11388	DB00276	ASW	nD3	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	Toprim,TOPRIM_C
P11388	DB00276	ASW	nD4	101.1.2	HTH	HTH	winged helix domain	DNA_topoisoIV
P11388	DB00276	ASW	nD5	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV

Show other predicted domains (35)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
1ZXM	e1zxmA2	212.1.1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	HSP90
	e1zxmB4	212.1.1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	HSP90
	e1zxmA1	225.1.1	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	SPOB_ab,SPOB_a
	e1zxmB3	225.1.1	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	SPOB_ab,SPOB_a
1ZXN	e1zxnC1	212.1.1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	HSP90
	e1zxnB4	212.1.1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	HSP90
	e1zxnD4	212.1.1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	HSP90
	e1zxnA4	212.1.1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	HSP90
	e1zxnC2	225.1.1	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	SPOB_ab,SPOB_a
	e1zxnB3	225.1.1	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	SPOB_ab,SPOB_a
	e1zxnD3	225.1.1	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	SPOB_ab,SPOB_a
	e1zxnA3	225.1.1	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	SPOB_ab,SPOB_a
4FM9	e4fm9A4	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e4fm9A7	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e4fm9A1	4012.1.1	SSHS domain	SSHS domain in type II DNA topoisomerase	SSHS domain in type II DNA topoisomerase	TOPRIM_C
	e4fm9A3	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e4fm9A6	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
4R1F	e4r1fA2	212.1.1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	HSP90
	e4r1fB2	212.1.1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	HSP90
	e4r1fC2	212.1.1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	HSP90
	e4r1fD2	212.1.1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	HSP90
	e4r1fA1	225.1.1	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	SPOB_ab,SPOB_a
	e4r1fB1	225.1.1	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	SPOB_ab,SPOB_a
	e4r1fC1	225.1.1	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	SPOB_ab,SPOB_a
	e4r1fD1	225.1.1	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	SPOB_ab,SPOB_a
5GWK	e5gwkA5	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e5gwkB2	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e5gwkA2	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e5gwkB3	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e5gwkA3	4012.1.1	SSHS domain	SSHS domain in type II DNA topoisomerase	SSHS domain in type II DNA topoisomerase	TOPRIM_C
	e5gwkB4	4012.1.1	SSHS domain	SSHS domain in type II DNA topoisomerase	SSHS domain in type II DNA topoisomerase	TOPRIM_C
	e5gwkA4	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e5gwkB5	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e5gwkA1	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
	e5gwkB1	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV

ECOD domains from experimental PDB structures interacting with ligand DB00276

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found