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1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID

P11388 — DNA topoisomerase 2-alpha

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Attributes

UniProt ID
P11388
Protein Name
DNA topoisomerase 2-alpha
Ligand Name
1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
DrugBank ID
DB00537
PDB Ligand Accession
CPF
ChEMBL ID
CHEMBL8
PubChem ID
2764; 4011971
InChIKey
MYSWGUAQZAJSOK-UHFFFAOYSA-N
SMILES
c1c2c(cc(c1F)N3CCNCC3)N(C=C(C2=O)C(=O)O)C4CC4
Drug Action
inhibitor
Affinity Metrics
ic50:100000 nM
ec50:30 nM