DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
DNA topoisomerase 2-alpha
Ligand Name
1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
MYSWGUAQZAJSOK-UHFFFAOYSA-N
SMILES
c1c2c(cc(c1F)N3CCNCC3)N(C=C(C2=O)C(=O)O)C4CC4
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: P11388_F1
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Color Legend
Unassigned regionsLigand / hetero atomsnD1nD2nD3nD4nD5
ECOD domains from AlphaFold model interacting with ligand DB00537
UniProtDrugBankPDB LigandECOD DomainRange Definition
P11388DB00537CPFnD126-265
P11388DB00537CPFnD2266-425
P11388DB00537CPFnD3426-715
P11388DB00537CPFnD4716-845
P11388DB00537CPFnD5846-1015