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Attributes

UniProt ID
Protein Name
DNA topoisomerase 2-alpha
Ligand Name
1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
FABPRXSRWADJSP-MEDUHNTESA-N
SMILES
COc1c2c(cc(c1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: P11388_F1
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Color Legend
Unassigned regionsLigand / hetero atomsnD1nD2nD3nD4nD5
ECOD domains from AlphaFold model interacting with ligand DB00218
UniProtDrugBankPDB LigandECOD DomainRange Definition
P11388DB00218MFXnD126-265
P11388DB00218MFXnD2266-425
P11388DB00218MFXnD3426-715
P11388DB00218MFXnD4716-845
P11388DB00218MFXnD5846-1015