Attributes
UniProt ID
Protein Name
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
Ligand Name
THIAMINE DIPHOSPHATE
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
AYEKOFBPNLCAJY-UHFFFAOYSA-O
SMILES
Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCOP(=O)(O)OP(=O)(O)O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 1DTW
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Color Legend
Unassigned regionsLigand / hetero atomse1dtwA1e1dtwB1e1dtwB2
ECOD domains from experimental PDB structures interacting with ligand TPP
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P12694 | n/a | TPP | 1dtw | e1dtwA1 | A:7-400 |
| P12694 | n/a | TPP | 1ols | e1olsA1 | A:6-400 |
| P12694 | n/a | TPP | 1olu | e1oluA1 | A:7-287,A:313-400 |
| P12694 | n/a | TPP | 1olx | e1olxA1 | A:6-400 |
| P12694 | n/a | TPP | 1u5b | e1u5bA1 | A:6-400 |
| P12694 | n/a | TPP | 1v11 | e1v11A1 | A:7-288,A:313-400 |
| P12694 | n/a | TPP | 1v16 | e1v16A1 | A:6-288,A:313-400 |
| P12694 | n/a | TPP | 1v1m | e1v1mA1 | A:6-400 |
| P12694 | n/a | TPP | 1x7w | e1x7wA1 | A:7-287,A:313-400 |
| P12694 | n/a | TPP | 1x7x | e1x7xA1 | A:6-287,A:313-400 |
| P12694 | n/a | TPP | 1x7y | e1x7yA1 | A:7-287,A:313-400 |
| P12694 | n/a | TPP | 1x7z | e1x7zA1 | A:6-400 |
| P12694 | n/a | TPP | 1x80 | e1x80A1 | A:7-287,A:313-400 |
| P12694 | n/a | TPP | 2bfb | e2bfbA1 | A:6-287,A:313-400 |
| P12694 | n/a | TPP | 2bfd | e2bfdA1 | A:6-293,A:313-400 |
| P12694 | n/a | TPP | 2bfe | e2bfeA1 | A:6-399 |