DrugDomain logoDrugDomain

(6P)-N-(1,3-dimethyl-1H-pyrazole-4-sulfonyl)-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide

P13569 — Cystic fibrosis transmembrane conductance regulator

← Back

Attributes

UniProt ID
P13569
Protein Name
Cystic fibrosis transmembrane conductance regulator
Ligand Name
(6P)-N-(1,3-dimethyl-1H-pyrazole-4-sulfonyl)-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
DrugBank ID
DB15444
PDB Ligand Accession
WJX
ChEMBL ID
CHEMBL4298128
PubChem ID
134587348
InChIKey
MVRHVFSOIWFBTE-INIZCTEOSA-N
SMILES
Cc1c(cn(n1)C)S(=O)(=O)NC(=O)c2ccc(nc2N3CC(CC3(C)C)C)n4ccc(n4)OCC(C)(C)C(F)(F)F
Drug Action
positive allosteric modulator
Affinity Metrics