Attributes
UniProt ID
Protein Name
Cystic fibrosis transmembrane conductance regulator
Ligand Name
(6P)-N-(1,3-dimethyl-1H-pyrazole-4-sulfonyl)-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
MVRHVFSOIWFBTE-INIZCTEOSA-N
SMILES
Cc1c(cn(n1)C)S(=O)(=O)NC(=O)c2ccc(nc2N3CC(CC3(C)C)C)n4ccc(n4)OCC(C)(C)C(F)(F)F
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 8EIG
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Color Legend
Unassigned regionsLigand / hetero atomse8eigA1e8eigA2e8eigA3e8eigA4
ECOD domains from experimental PDB structures interacting with ligand DB15444
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P13569 | DB15444 | WJX | 8eig | e8eigA3 | A:3-381 |
| P13569 | DB15444 | WJX | 8eig | e8eigA4 | A:846-887,A:909-1173 |
| P13569 | DB15444 | WJX | 8eio | e8eioA2 | A:1-381 |
| P13569 | DB15444 | WJX | 8eio | e8eioA3 | A:846-887,A:909-1173 |
| P13569 | DB15444 | WJX | 8eiq | e8eiqA3 | A:1-381 |
| P13569 | DB15444 | WJX | 8eiq | e8eiqA4 | A:846-887,A:909-1173 |