DrugDomain logoDrugDomain

(3R,5R)-7-((1R,2R,6S,8R,8AS)-2,6-DIMETHYL-8-{[(2R)-2-METHYLBUTANOYL]OXY}-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)-3,5-DIHYDROXYHEPTANOIC ACID

P13702 3-hydroxy-3-methylglutaryl-coenzyme A reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB03785

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB03785

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P13702DB037851t02LVAA429e1t02A2Alpha-beta plaitsHMG-CoA reductaseSubstrate-binding domain of HMG-CoA reductaseHMG-CoA_red
P13702DB037851t02LVAA429e1t02B1Alpha-beta plaitsHMG-CoA reductaseNAD-binding domain of HMG-CoA reductaseHMG-CoA_red