Attributes
UniProt ID
Protein Name
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Ligand Name
(R)-MEVALONATE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
KJTLQQUUPVSXIM-ZCFIWIBFSA-M
SMILES
CC(CCO)(CC(=O)[O-])O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 1QAY
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse1qayA1e1qayA2e1qayB1e1qayB2
ECOD domains from experimental PDB structures interacting with ligand DB03518
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P13702 | DB03518 | MEV | 1qay | e1qayA2 | A:4-110,A:221-379 |
| P13702 | DB03518 | MEV | 1qay | e1qayB1 | B:611-720 |
| P13702 | DB03518 | MEV | 1r31 | e1r31A1 | A:111-220 |
| P13702 | DB03518 | MEV | 1r31 | e1r31A2 | A:3-110,A:221-378 |
| P13702 | DB03518 | MEV | 1r31 | e1r31B1 | B:611-720 |
| P13702 | DB03518 | MEV | 1r31 | e1r31B2 | B:503-610,B:721-877 |
| P13702 | DB03518 | MEV | 4i6y | e4i6yA1 | A:111-220 |
| P13702 | DB03518 | MEV | 4i6y | e4i6yA2 | A:3-110,A:221-376 |
| P13702 | DB03518 | MEV | 4i6y | e4i6yB1 | B:611-720 |
| P13702 | DB03518 | MEV | 4i6y | e4i6yB2 | B:503-610,B:721-879 |