(E,4S)-4-[[5-[2-[2,6-bis(azanyl)-4-oxidanylidene-1H-pyrimidin-5-yl]ethanoylamino]-3-fluoranyl-pyridin-2-yl]carbonylamino]pent-2-enedioic acid
P13995 — Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand KUN
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand KUN
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P13995 | n/a | 6s4f | KUN | A | 401 | e6s4fA1 | Rossmann-like | Rossmann-related | NAD(P)-binding Rossmann-fold domains | THF_DHG_CYH_C |
| P13995 | n/a | 6s4f | KUN | A | 401 | e6s4fA2 | Flavodoxin-like | Class I glutamine amidotransferase-like | Aminoacid dehydrogenase-like, N-terminal domain | THF_DHG_CYH |
| P13995 | n/a | 6s4f | KUN | B | 401 | e6s4fB1 | Rossmann-like | Rossmann-related | NAD(P)-binding Rossmann-fold domains | THF_DHG_CYH_C |
| P13995 | n/a | 6s4f | KUN | B | 401 | e6s4fB2 | Flavodoxin-like | Class I glutamine amidotransferase-like | Aminoacid dehydrogenase-like, N-terminal domain | THF_DHG_CYH |