6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one
P14618 — Pyruvate kinase PKM
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB07628
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand DB07628
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P14618 | DB07628 | 3h6o | D8G | B | 550 | e3h6oA1 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | PK |
| P14618 | DB07628 | 3h6o | D8G | B | 550 | e3h6oA2 | PK C-terminal domain-like | PK C-terminal domain-like | PK C-terminal domain-like | PK_C |
| P14618 | DB07628 | 3h6o | D8G | B | 550 | e3h6oB1 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | PK |
| P14618 | DB07628 | 3h6o | D8G | C | 550 | e3h6oC1 | PK C-terminal domain-like | PK C-terminal domain-like | PK C-terminal domain-like | PK_C |
| P14618 | DB07628 | 3h6o | D8G | C | 550 | e3h6oC2 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | PK |
| P14618 | DB07628 | 3h6o | D8G | C | 550 | e3h6oD1 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | PK |
| P14618 | DB07628 | 3h6o | D8G | C | 550 | e3h6oD2 | PK C-terminal domain-like | PK C-terminal domain-like | PK C-terminal domain-like | PK_C |