Attributes
UniProt ID
Protein Name
Pyruvate kinase PKM
Ligand Name
N-(4-{[4-(pyrazin-2-yl)piperazin-1-yl]carbonyl}phenyl)quinoline-8-sulfonamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
BNGHGURIVRPDJB-UHFFFAOYSA-N
SMILES
c1cc2cccnc2c(c1)S(=O)(=O)Nc3ccc(cc3)C(=O)N4CCN(CC4)c5cnccn5
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 4G1N
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Color Legend
Unassigned regionsLigand / hetero atomse4g1nA1e4g1nA2e4g1nA3e4g1nB1e4g1nB2e4g1nB3e4g1nC1e4g1nC2e4g1nC3e4g1nD1e4g1nD2e4g1nD3
ECOD domains from experimental PDB structures interacting with ligand NZT
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P14618 | n/a | NZT | 4g1n | e4g1nA2 | A:14-116,A:219-396 |
| P14618 | n/a | NZT | 4g1n | e4g1nA3 | A:397-531 |
| P14618 | n/a | NZT | 4g1n | e4g1nB2 | B:14-116,B:219-396 |
| P14618 | n/a | NZT | 4g1n | e4g1nC2 | C:14-116,C:219-396 |
| P14618 | n/a | NZT | 4g1n | e4g1nC3 | C:397-531 |
| P14618 | n/a | NZT | 4g1n | e4g1nD2 | D:397-531 |
| P14618 | n/a | NZT | 4g1n | e4g1nD3 | D:14-116,D:219-396 |