SERINE

P14618 — Pyruvate kinase PKM

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB00133

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB00133

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P14618	DB00133	4b2d	SER	A	1532	e4b2dA2	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	4b2d	SER	A	1532	e4b2dA4	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	4b2d	SER	B	1532	e4b2dB1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	4b2d	SER	B	1532	e4b2dB2	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	4b2d	SER	C	1532	e4b2dC1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	4b2d	SER	C	1532	e4b2dC3	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	4b2d	SER	D	1532	e4b2dD1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	4b2d	SER	D	1532	e4b2dD3	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	4yj5	SER	A	603	e4yj5A1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	4yj5	SER	A	603	e4yj5A3	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	4yj5	SER	B	603	e4yj5B2	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	4yj5	SER	B	603	e4yj5B3	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	4yj5	SER	C	603	e4yj5C1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	4yj5	SER	C	603	e4yj5C2	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	4yj5	SER	D	603	e4yj5D1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	4yj5	SER	D	603	e4yj5D2	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	5x0i	SER	A	602	e5x0iA2	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	5x0i	SER	A	602	e5x0iA3	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	5x0i	SER	B	602	e5x0iB2	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	5x0i	SER	B	602	e5x0iB3	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	5x0i	SER	C	602	e5x0iC2	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	5x0i	SER	C	602	e5x0iC3	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	5x0i	SER	D	602	e5x0iD1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	5x0i	SER	D	602	e5x0iD3	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	6gg6	SER	A	603	e6gg6A1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	6gg6	SER	A	603	e6gg6A3	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	6gg6	SER	B	603	e6gg6B1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	6gg6	SER	B	603	e6gg6B2	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	6gg6	SER	C	603	e6gg6C1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	6gg6	SER	C	603	e6gg6C3	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	6gg6	SER	D	603	e6gg6D1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	6gg6	SER	D	603	e6gg6D3	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	6gg6	SER	E	603	e6gg6E1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	6gg6	SER	E	603	e6gg6E2	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	6gg6	SER	F	603	e6gg6F1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	6gg6	SER	F	603	e6gg6F2	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	6gg6	SER	G	603	e6gg6G1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	6gg6	SER	G	603	e6gg6G2	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	6gg6	SER	H	603	e6gg6H2	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	6gg6	SER	H	603	e6gg6H3	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	6jfb	SER	A	601	e6jfbA1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	6jfb	SER	A	601	e6jfbA2	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	6jfb	SER	B	601	e6jfbB1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	6jfb	SER	B	601	e6jfbB3	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	6jfb	SER	C	601	e6jfbC1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	6jfb	SER	C	601	e6jfbC3	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	6jfb	SER	D	601	e6jfbD1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	6jfb	SER	D	601	e6jfbD3	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	6nub	SER	A	601	e6nubA2	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	6nub	SER	A	601	e6nubA3	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK
P14618	DB00133	6nub	SER	B	601	e6nubB2	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
P14618	DB00133	6nub	SER	B	601	e6nubB3	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK