1,4-DIETHYLENE DIOXIDE

P14735 — Insulin-degrading enzyme

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB03316

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB03316

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P14735	DB03316	2g47	DIO	A	2000	e2g47A12	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16_C,Peptidase_M16_M
P14735	DB03316	2g47	DIO	A	2000	e2g47A2	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16,Peptidase_M16_C
P14735	DB03316	2g47	DIO	B	2001	e2g47B12	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16_C,Peptidase_M16_M
P14735	DB03316	2g47	DIO	B	2001	e2g47B4	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16,Peptidase_M16_C
P14735	DB03316	2jg4	DIO	A	2014	e2jg4A13	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	PqqF-like_C_4
P14735	DB03316	2jg4	DIO	B	2014	e2jg4B13	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	PqqF-like_C_4
P14735	DB03316	2wc0	DIO	A	3016	e2wc0A12	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16_C,Peptidase_M16_M
P14735	DB03316	2wc0	DIO	B	3016	e2wc0B9	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16_C,Peptidase_M16_M
P14735	DB03316	3cww	DIO	A	4006	e3cwwA1	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16,Peptidase_M16_C
P14735	DB03316	3cww	DIO	A	4006	e3cwwA12	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16_C,Peptidase_M16_M
P14735	DB03316	3cww	DIO	B	4005	e3cwwB11	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16_M
P14735	DB03316	3cww	DIO	B	4005	e3cwwB13	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	PqqF-like_C_4
P14735	DB03316	3e4a	DIO	A	2003	e3e4aA13	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	PqqF-like_C_4
P14735	DB03316	3e4a	DIO	B	2006	e3e4aB11	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16_M
P14735	DB03316	3e4a	DIO	B	2006	e3e4aB13	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	PqqF-like_C_4
P14735	DB03316	3h44	DIO	A	2002	e3h44A1	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16,Peptidase_M16_C
P14735	DB03316	3h44	DIO	A	2002	e3h44A12	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16_C,Peptidase_M16_M
P14735	DB03316	3h44	DIO	B	2002	e3h44B1	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16,Peptidase_M16_C
P14735	DB03316	3h44	DIO	B	2002	e3h44B12	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16_C,Peptidase_M16_M
P14735	DB03316	3n56	DIO	A	4001	e3n56A1	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16,Peptidase_M16_C
P14735	DB03316	3n56	DIO	A	4001	e3n56A12	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16_C,Peptidase_M16_M
P14735	DB03316	3n56	DIO	B	4006	e3n56B1	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16,Peptidase_M16_C
P14735	DB03316	3n56	DIO	B	4006	e3n56B12	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16_C,Peptidase_M16_M
P14735	DB03316	3ofi	DIO	A	2013	e3ofiA13	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	PqqF-like_C_4
P14735	DB03316	3ofi	DIO	B	2014	e3ofiB13	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	PqqF-like_C_4
P14735	DB03316	4nxo	DIO	B	1111	e4nxoB1	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16_C,Peptidase_M16_M
P14735	DB03316	6eds	DIO	A	1104	e6edsA3	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16_M
P14735	DB03316	6eds	DIO	B	1103	e6edsB2	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16_M
P14735	DB03316	7k1d	DIO	A	1105	e7k1dA1	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16,Peptidase_M16_C
P14735	DB03316	7k1d	DIO	B	1105	e7k1dB1	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16,Peptidase_M16_C
P14735	DB03316	7k1e	DIO	A	1105	e7k1eA1	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16,Peptidase_M16_C
P14735	DB03316	7k1e	DIO	B	1105	e7k1eB1	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16,Peptidase_M16_C
P14735	DB03316	7k1f	DIO	A	1105	e7k1fA1	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16,Peptidase_M16_C
P14735	DB03316	7k1f	DIO	B	1105	e7k1fB1	LuxS, MPP, ThrRS/AlaRS common domain	LuxS, MPP, ThrRS/AlaRS common domain	LuxS/MPP-like metallohydrolase	Peptidase_M16,Peptidase_M16_C