DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Insulin-degrading enzyme
Ligand Name
[(8R,9S,10S)-9-(2',3'-dimethyl[1,1'-biphenyl]-4-yl)-6-{[2-(trifluoromethyl)phenyl]sulfonyl}-1,6-diazabicyclo[6.2.0]decan-10-yl]methanol
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
OOPXWKPIZJCPGQ-GKRYNVPLSA-N
SMILES
Cc1cccc(c1C)c2ccc(cc2)C3C4CN(CCCCN4C3CO)S(=O)(=O)c5ccccc5C(F)(F)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 6BYZ
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Color Legend
Unassigned regionsLigand / hetero atomse6byzA1e6byzA2e6byzA3e6byzA4e6byzB1e6byzB2e6byzB3e6byzB4
ECOD domains from experimental PDB structures interacting with ligand J18
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P14735n/aJ186byze6byzA2A:43-286
P14735n/aJ186byze6byzA4A:287-527
P14735n/aJ186byze6byzB2B:44-286
P14735n/aJ186byze6byzB3B:287-527