DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Insulin-degrading enzyme
Ligand Name
3,4-difluoro-N-[(1S)-1-{1-[(2R)-4-(hydroxyamino)-4-oxo-1-(5,6,7,8-tetrahydronaphthalen-2-yl)butan-2-yl]-1H-1,2,3-triazol-4-yl}ethyl]benzamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
VQGQRXDQPMXXSZ-MGPUTAFESA-N
SMILES
CC(c1cn(nn1)C(Cc2ccc3c(c2)CCCC3)CC(=O)NO)NC(=O)c4ccc(c(c4)F)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 7K1E
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Color Legend
Unassigned regionsLigand / hetero atomse7k1eA1e7k1eA2e7k1eA3e7k1eA4e7k1eB1e7k1eB2e7k1eB3e7k1eB4
ECOD domains from experimental PDB structures interacting with ligand VQG
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P14735n/aVQG7k1ee7k1eA1A:66-285
P14735n/aVQG7k1ee7k1eA3A:767-1012
P14735n/aVQG7k1ee7k1eB1B:39-286
P14735n/aVQG7k1ee7k1eB3B:767-1011