DrugDomain logoDrugDomain

Attributes

UniProt ID
P14779
Protein Name
Bifunctional cytochrome P450/NADPH--P450 reductase
Ligand Name
PROTOPORPHYRIN IX CONTAINING FE
DrugBank ID
DB18267
PDB Ligand Accession
HEM
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
KABFMIBPWCXCRK-RGGAHWMASA-L
SMILES
Cc1c2n3c(c1CCC(=O)O)C=C4C(=C(C5=[N]4[Fe]36[N]7=C(C=C8N6C(=C5)C(=C8C)C=C)C(=C(C7=C2)C)C=C)C)CCC(=O)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 1BU7
Open File
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse1bu7A1e1bu7B1
ECOD domains from experimental PDB structures interacting with ligand DB18267
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P14779DB18267HEM1bu7e1bu7A1A:3-455
P14779DB18267HEM1bu7e1bu7B1B:3-455
P14779DB18267HEM1bvye1bvyA1A:20-455
P14779DB18267HEM1bvye1bvyB1B:21-455
P14779DB18267HEM1fage1fagA1A:3-455
P14779DB18267HEM1fage1fagB1B:3-455
P14779DB18267HEM1fage1fagC1C:3-455
P14779DB18267HEM1fage1fagD1D:3-455
P14779DB18267HEM1fahe1fahA1A:3-455
P14779DB18267HEM1fahe1fahB1B:3-455
P14779DB18267HEM1jmee1jmeA1A:3-455
P14779DB18267HEM1jmee1jmeB1B:3-455
P14779DB18267HEM1jpze1jpzA1A:3-455
P14779DB18267HEM1jpze1jpzB1B:3-455
P14779DB18267HEM1p0ve1p0vA1A:3-455
P14779DB18267HEM1p0ve1p0vB1B:3-455
P14779DB18267HEM1p0we1p0wA1A:3-455
P14779DB18267HEM1p0we1p0wB1B:3-455
P14779DB18267HEM1p0xe1p0xA1A:3-455
P14779DB18267HEM1p0xe1p0xB1B:3-455
P14779DB18267HEM1smie1smiA1A:3-455
P14779DB18267HEM1smie1smiB1B:3-455
P14779DB18267HEM1smje1smjA1A:3-455
P14779DB18267HEM1smje1smjB1B:3-455
P14779DB18267HEM1smje1smjC1C:3-455
P14779DB18267HEM1smje1smjD1D:3-455
P14779DB18267HEM1yqoe1yqoA1A:3-455
P14779DB18267HEM1yqoe1yqoB1B:3-455
P14779DB18267HEM1yqpe1yqpA1A:3-455
P14779DB18267HEM1yqpe1yqpB1B:3-455
P14779DB18267HEM1zo4e1zo4A1A:1-456
P14779DB18267HEM1zo4e1zo4B1B:1-457
P14779DB18267HEM1zo9e1zo9A1A:3-455
P14779DB18267HEM1zo9e1zo9B1B:3-455
P14779DB18267HEM1zoae1zoaA1A:2-458
P14779DB18267HEM1zoae1zoaB1B:2-458
P14779DB18267HEM2bmhe2bmhA1A:3-455
P14779DB18267HEM2bmhe2bmhB1B:3-455
P14779DB18267HEM2hpde2hpdA1A:3-455
P14779DB18267HEM2hpde2hpdB1B:3-455
P14779DB18267HEM2ij2e2ij2A1A:3-455
P14779DB18267HEM2ij2e2ij2B1B:5-455
P14779DB18267HEM2ij3e2ij3A1A:3-455
P14779DB18267HEM2ij3e2ij3B1B:2-455
P14779DB18267HEM2ij4e2ij4A1A:1-456
P14779DB18267HEM2ij4e2ij4B1B:2-458
P14779DB18267HEM2j1me2j1mA1A:3-455
P14779DB18267HEM2j1me2j1mB1B:3-455
P14779DB18267HEM2j4se2j4sA1A:3-455
P14779DB18267HEM2j4se2j4sB1B:3-455
P14779DB18267HEM2nnbe2nnbA1A:3-455
P14779DB18267HEM2nnbe2nnbB1B:3-455
P14779DB18267HEM2uwhe2uwhA1A:1-458
P14779DB18267HEM2uwhe2uwhB1B:1-458
P14779DB18267HEM2uwhe2uwhC1C:1-458
P14779DB18267HEM2uwhe2uwhD1D:1-458
P14779DB18267HEM2uwhe2uwhE1E:1-458
P14779DB18267HEM2uwhe2uwhF1F:1-458
P14779DB18267HEM2x7ye2x7yA1A:1-455
P14779DB18267HEM2x7ye2x7yB1B:1-455
P14779DB18267HEM2x80e2x80A1A:1-455
P14779DB18267HEM2x80e2x80B1B:1-455
P14779DB18267HEM3bene3benA1A:4-455
P14779DB18267HEM3bene3benB1B:4-455
P14779DB18267HEM3cbde3cbdA1A:1-455
P14779DB18267HEM3cbde3cbdB1B:1-455
P14779DB18267HEM3dgie3dgiA1A:3-455
P14779DB18267HEM3dgie3dgiB1B:3-180,B:205-455
P14779DB18267HEM3ekbe3ekbA1A:1-456
P14779DB18267HEM3ekbe3ekbB1B:2-458
P14779DB18267HEM3ekde3ekdA1A:1-457
P14779DB18267HEM3ekde3ekdB1B:2-458
P14779DB18267HEM3ekfe3ekfA1A:1-456
P14779DB18267HEM3ekfe3ekfB1B:2-458
P14779DB18267HEM3hf2e3hf2A1A:5-455
P14779DB18267HEM3hf2e3hf2B1B:5-455
P14779DB18267HEM3kx3e3kx3A1A:3-458
P14779DB18267HEM3kx3e3kx3B1B:3-458
P14779DB18267HEM3kx4e3kx4A1A:3-455
P14779DB18267HEM3kx4e3kx4B1B:2-455
P14779DB18267HEM3kx5e3kx5A1A:5-459
P14779DB18267HEM3kx5e3kx5B1B:3-457
P14779DB18267HEM3m4ve3m4vA1A:5-455
P14779DB18267HEM3m4ve3m4vB1B:5-455
P14779DB18267HEM3nple3nplA1A:5-460
P14779DB18267HEM3nple3nplB1B:5-460
P14779DB18267HEM3psxe3psxA1A:4-172,A:211-455
P14779DB18267HEM3psxe3psxB1B:5-175,B:212-456
P14779DB18267HEM3wspe3wspA1A:3-455
P14779DB18267HEM3wspe3wspB1B:3-455
P14779DB18267HEM4dtwe4dtwA1A:1-455
P14779DB18267HEM4dtwe4dtwB1B:1-455
P14779DB18267HEM4dtye4dtyA1A:1-455
P14779DB18267HEM4dtye4dtyB1B:1-455
P14779DB18267HEM4dtze4dtzA1A:1-455
P14779DB18267HEM4dtze4dtzB1B:1-455
P14779DB18267HEM4du2e4du2A1A:0-455
P14779DB18267HEM4du2e4du2B1B:0-455
P14779DB18267HEM4duae4duaA1A:1-455
P14779DB18267HEM4duae4duaB1B:1-455
P14779DB18267HEM4dube4dubA1A:2-457
P14779DB18267HEM4dube4dubB1B:0-455
P14779DB18267HEM4duce4ducA1A:0-455
P14779DB18267HEM4duce4ducB1B:0-455
P14779DB18267HEM4dude4dudA1A:1-455
P14779DB18267HEM4dude4dudB1B:1-455
P14779DB18267HEM4duee4dueA1A:1-455
P14779DB18267HEM4duee4dueB1B:1-455
P14779DB18267HEM4dufe4dufA1A:1-455
P14779DB18267HEM4dufe4dufB1B:1-455
P14779DB18267HEM4dufe4dufC1C:1-455
P14779DB18267HEM4dufe4dufD1D:1-455
P14779DB18267HEM4h23e4h23A1A:2-455
P14779DB18267HEM4h23e4h23B1B:2-455
P14779DB18267HEM4h24e4h24A1A:1-457
P14779DB18267HEM4h24e4h24B1B:1-457
P14779DB18267HEM4h24e4h24C1C:1-456
P14779DB18267HEM4h24e4h24D1D:4-458
P14779DB18267HEM4hgfe4hgfA1A:1-442
P14779DB18267HEM4hgfe4hgfB1B:1-441
P14779DB18267HEM4hgge4hggA1A:1-435
P14779DB18267HEM4hgge4hggB1B:1-441
P14779DB18267HEM4hghe4hghA1A:1-455
P14779DB18267HEM4hghe4hghB1B:1-455
P14779DB18267HEM4hgie4hgiA1A:1-455
P14779DB18267HEM4hgie4hgiB1B:1-453
P14779DB18267HEM4hgje4hgjA1A:1-448
P14779DB18267HEM4hgje4hgjB1B:1-451
P14779DB18267HEM4kewe4kewA1A:3-455
P14779DB18267HEM4kewe4kewB1B:3-455
P14779DB18267HEM4keye4keyA1A:3-455
P14779DB18267HEM4keye4keyB1B:3-455
P14779DB18267HEM4kf0e4kf0A1A:3-457
P14779DB18267HEM4kf0e4kf0B1B:3-457
P14779DB18267HEM4kf2e4kf2A1A:3-457
P14779DB18267HEM4kf2e4kf2B1B:3-456
P14779DB18267HEM4kpae4kpaA1A:-5-458
P14779DB18267HEM4kpbe4kpbA1A:5-458
P14779DB18267HEM4kpbe4kpbB1B:4-458
P14779DB18267HEM4o4pe4o4pA1A:3-455
P14779DB18267HEM4o4pe4o4pB1B:4-455
P14779DB18267HEM4rsne4rsnA1A:-4-455
P14779DB18267HEM4rsne4rsnB1B:-4-455
P14779DB18267HEM4wg2e4wg2A1A:4-464
P14779DB18267HEM4wg2e4wg2B1B:3-458
P14779DB18267HEM4wg2e4wg2C1C:4-463
P14779DB18267HEM4zf6e4zf6A1A:1-460
P14779DB18267HEM4zf8e4zf8A1A:1-460
P14779DB18267HEM4zfae4zfaA1A:1-460
P14779DB18267HEM4zfbe4zfbA1A:1-460
P14779DB18267HEM5b2ue5b2uA1A:3-455
P14779DB18267HEM5b2ue5b2uB1B:3-455
P14779DB18267HEM5b2ve5b2vA1A:3-455
P14779DB18267HEM5b2ve5b2vB1B:3-455
P14779DB18267HEM5b2we5b2wA1A:4-455
P14779DB18267HEM5b2we5b2wB1B:4-455
P14779DB18267HEM5b2xe5b2xA1A:3-455
P14779DB18267HEM5b2xe5b2xB1B:3-455
P14779DB18267HEM5b2ye5b2yA1A:4-455
P14779DB18267HEM5b2ye5b2yB1B:4-455
P14779DB18267HEM5dype5dypA1A:2-455
P14779DB18267HEM5dype5dypC1C:1-456
P14779DB18267HEM5dyze5dyzA1A:2-456
P14779DB18267HEM5dyze5dyzC1C:2-455
P14779DB18267HEM5e78e5e78A1A:3-455
P14779DB18267HEM5e78e5e78B1B:2-455
P14779DB18267HEM5e7ye5e7yA1A:5-455
P14779DB18267HEM5e7ye5e7yB1B:4-455
P14779DB18267HEM5jq2e5jq2A1A:1-457
P14779DB18267HEM5jq2e5jq2B1B:1-459
P14779DB18267HEM5jtde5jtdA1A:1-458
P14779DB18267HEM5jtde5jtdB1B:1-458
P14779DB18267HEM5xa3e5xa3A1A:3-455
P14779DB18267HEM5xa3e5xa3B1B:3-455
P14779DB18267HEM5xa3e5xa3C1C:3-455
P14779DB18267HEM5xa3e5xa3D1D:3-455
P14779DB18267HEM5xhje5xhjA1A:3-455
P14779DB18267HEM5xhje5xhjB1B:3-455
P14779DB18267HEM6h1oe6h1oA1A:2-457
P14779DB18267HEM6h1oe6h1oB1B:1-457
P14779DB18267HEM6h1se6h1sA1A:5-457
P14779DB18267HEM6h1se6h1sB1B:2-456
P14779DB18267HEM6iaoe6iaoA1A:3-457
P14779DB18267HEM6iaoe6iaoB1B:5-456
P14779DB18267HEM6iaoe6iaoC1C:-5-457
P14779DB18267HEM6iaoe6iaoD1D:4-458
P14779DB18267HEM6jlve6jlvA1A:1-455
P14779DB18267HEM6jlve6jlvB1B:1-455
P14779DB18267HEM6jo1e6jo1A1A:3-455
P14779DB18267HEM6jo1e6jo1B1B:3-455
P14779DB18267HEM6js8e6js8A1A:1-455
P14779DB18267HEM6js8e6js8B1B:2-455
P14779DB18267HEM6k3qe6k3qA1A:3-455
P14779DB18267HEM6k3qe6k3qB1B:3-455
P14779DB18267HEM6k58e6k58A1A:1-455
P14779DB18267HEM6k58e6k58B1B:2-455
P14779DB18267HEM6l1ae6l1aA1A:2-455
P14779DB18267HEM6l1ae6l1aB1B:2-455
P14779DB18267HEM6l1be6l1bA1A:2-455
P14779DB18267HEM6l1be6l1bB1B:2-455
P14779DB18267HEM6ly4e6ly4A1A:3-455
P14779DB18267HEM7ckne7cknA1A:2-455
P14779DB18267HEM7ckne7cknB1B:2-455
P14779DB18267HEM7cone7conA1A:2-455
P14779DB18267HEM7cone7conB1B:2-455
P14779DB18267HEM7cooe7cooA1A:2-455
P14779DB18267HEM7cooe7cooB1B:2-455
P14779DB18267HEM7cp8e7cp8A1A:2-455
P14779DB18267HEM7cp8e7cp8B1B:2-455
P14779DB18267HEM7cvre7cvrA1A:3-455
P14779DB18267HEM7cvre7cvrB1B:3-455
P14779DB18267HEM7cx6e7cx6A1A:1-455
P14779DB18267HEM7cx6e7cx6B1B:2-455
P14779DB18267HEM7cx8e7cx8A1A:1-455
P14779DB18267HEM7cx8e7cx8B1B:1-455
P14779DB18267HEM7czie7cziA1A:2-455
P14779DB18267HEM7czie7cziB1B:2-455
P14779DB18267HEM7d0te7d0tA1A:2-455
P14779DB18267HEM7d0te7d0tB1B:2-455
P14779DB18267HEM7d0ue7d0uA1A:2-455
P14779DB18267HEM7d0ue7d0uB1B:2-455
P14779DB18267HEM7d1fe7d1fA1A:2-455
P14779DB18267HEM7d1fe7d1fB1B:2-455
P14779DB18267HEM7e46e7e46A1A:2-455
P14779DB18267HEM7e46e7e46B1B:2-455
P14779DB18267HEM7egne7egnA1A:3-455
P14779DB18267HEM7egne7egnB1B:3-455
P14779DB18267HEM7w97e7w97A1A:4-455
P14779DB18267HEM7w97e7w97B1B:4-455
P14779DB18267HEM7xzke7xzkA1A:3-455
P14779DB18267HEM7xzke7xzkB1B:3-455
P14779DB18267HEM7y0pe7y0pA1A:3-455
P14779DB18267HEM7y0pe7y0pB1B:3-455
P14779DB18267HEM7y0qe7y0qA1A:3-455
P14779DB18267HEM7y0qe7y0qB1B:3-455
P14779DB18267HEM7y0re7y0rA1A:3-455
P14779DB18267HEM7y0re7y0rB1B:3-455
P14779DB18267HEM7y0se7y0sA1A:3-455
P14779DB18267HEM7y0se7y0sB1B:3-455
P14779DB18267HEM7y0te7y0tA1A:3-455
P14779DB18267HEM7y0te7y0tB1B:3-455
P14779DB18267HEM7y0ue7y0uA1A:3-455
P14779DB18267HEM7y0ue7y0uB1B:3-455
P14779DB18267HEM7y9je7y9jA1A:4-457
P14779DB18267HEM7y9je7y9jB1B:4-457
P14779DB18267HEM7y9ke7y9kA1A:4-456
P14779DB18267HEM7y9ke7y9kB1B:4-457
P14779DB18267HEM7y9le7y9lA1A:5-455
P14779DB18267HEM7y9le7y9lB1B:5-455
P14779DB18267HEM7y9me7y9mA1A:5-455
P14779DB18267HEM7y9me7y9mB1B:5-182,B:207-455
P14779DB18267HEM7yd9e7yd9A1A:3-456
P14779DB18267HEM7yd9e7yd9B1B:3-456
P14779DB18267HEM7ydae7ydaA1A:3-456
P14779DB18267HEM7ydae7ydaB1B:3-456
P14779DB18267HEM7ydbe7ydbA1A:4-455
P14779DB18267HEM7ydbe7ydbB1B:4-455
P14779DB18267HEM7ydce7ydcA1A:3-456
P14779DB18267HEM7ydce7ydcB1B:4-456
P14779DB18267HEM7ydde7yddA1A:3-456
P14779DB18267HEM7ydde7yddB1B:3-455
P14779DB18267HEM7ydee7ydeA1A:3-456
P14779DB18267HEM7ydee7ydeB1B:3-456
P14779DB18267HEM7ydle7ydlA1A:3-455
P14779DB18267HEM7ydle7ydlB1B:4-455
P14779DB18267HEM7yfte7yftA1A:5-455
P14779DB18267HEM7yfte7yftB1B:4-455
P14779DB18267HEM7yjde7yjdA1A:3-455
P14779DB18267HEM7yjde7yjdB1B:3-455
P14779DB18267HEM7yjee7yjeA1A:2-455
P14779DB18267HEM7yjee7yjeB1B:2-455
P14779DB18267HEM7yjfe7yjfA1A:4-455
P14779DB18267HEM7yjfe7yjfB1B:4-455
P14779DB18267HEM7yjge7yjgA1A:2-456
P14779DB18267HEM7yjge7yjgB1B:2-455
P14779DB18267HEM7yjhe7yjhA1A:5-455
P14779DB18267HEM7yjhe7yjhB1B:5-455
P14779DB18267HEM8dmee8dmeA1A:3-469
P14779DB18267HEM8dmee8dmeB1B:3-469
P14779DB18267HEM8dmge8dmgA1A:3-469
P14779DB18267HEM8dmge8dmgB1B:3-469