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Attributes

UniProt ID
P14902
Protein Name
Indoleamine 2,3-dioxygenase 1
Ligand Name
PROTOPORPHYRIN IX CONTAINING FE
DrugBank ID
DB18267
PDB Ligand Accession
HEM
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
KABFMIBPWCXCRK-RGGAHWMASA-L
SMILES
Cc1c2n3c(c1CCC(=O)O)C=C4C(=C(C5=[N]4[Fe]36[N]7=C(C=C8N6C(=C5)C(=C8C)C=C)C(=C(C7=C2)C)C=C)C)CCC(=O)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Mol*
Structure: 2D0T
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Color Legend
Unassigned regionsLigand / hetero atomse2d0tA1e2d0tA2e2d0tB1e2d0tB2
ECOD domains from experimental PDB structures interacting with ligand DB18267
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P14902DB18267HEM2d0te2d0tA1A:123-360,A:380-403
P14902DB18267HEM2d0te2d0tB1B:122-402
P14902DB18267HEM2d0ue2d0uA1A:122-402
P14902DB18267HEM2d0ue2d0uB1B:122-402
P14902DB18267HEM4pk5e4pk5A1A:122-360,A:380-403
P14902DB18267HEM4pk5e4pk5B1B:122-360,B:380-403
P14902DB18267HEM4pk6e4pk6A1A:122-360,A:380-403
P14902DB18267HEM4pk6e4pk6B1B:122-360,B:380-403
P14902DB18267HEM4u72e4u72A2A:123-360,A:380-403
P14902DB18267HEM4u72e4u72B2B:122-360,B:380-403
P14902DB18267HEM4u74e4u74A2A:123-360,A:380-403
P14902DB18267HEM4u74e4u74B2B:122-360,B:380-403
P14902DB18267HEM5ek2e5ek2A2A:123-360,A:380-403
P14902DB18267HEM5ek2e5ek2B2B:123-360,B:380-403
P14902DB18267HEM5ek3e5ek3A2A:123-360,A:380-403
P14902DB18267HEM5ek3e5ek3B1B:123-360,B:380-403
P14902DB18267HEM5ek4e5ek4A2A:122-360,A:380-401
P14902DB18267HEM5ek4e5ek4B2B:122-360,B:380-403
P14902DB18267HEM5etwe5etwA1A:122-360,A:380-400
P14902DB18267HEM5etwe5etwB1B:122-358,B:381-401
P14902DB18267HEM5whre5whrA1A:123-360,A:380-402
P14902DB18267HEM5whre5whrB2B:123-360,B:380-401
P14902DB18267HEM5wmue5wmuA2A:123-360,A:380-403
P14902DB18267HEM5wmue5wmuB1B:123-360,B:380-401
P14902DB18267HEM5wmve5wmvA1A:123-360,A:380-403
P14902DB18267HEM5wmve5wmvB1B:123-360,B:380-403
P14902DB18267HEM5wmwe5wmwA2A:123-360,A:380-401
P14902DB18267HEM5wmwe5wmwB1B:123-360,B:380-403
P14902DB18267HEM5wmxe5wmxA2A:123-360,A:380-403
P14902DB18267HEM5wmxe5wmxB2B:123-360,B:380-403
P14902DB18267HEM5wn8e5wn8A1A:123-360,A:380-402
P14902DB18267HEM5wn8e5wn8B2B:122-360,B:381-402
P14902DB18267HEM5xe1e5xe1A1A:122-360,A:382-401
P14902DB18267HEM5xe1e5xe1B2B:123-360,B:380-401
P14902DB18267HEM6azue6azuA1A:122-360,A:381-401
P14902DB18267HEM6azue6azuB2B:122-360,B:382-401
P14902DB18267HEM6azue6azuC1C:122-360,C:381-401
P14902DB18267HEM6azue6azuD1D:122-360,D:381-401
P14902DB18267HEM6cxue6cxuA1A:123-360,A:380-403
P14902DB18267HEM6cxue6cxuB2B:123-360,B:380-403
P14902DB18267HEM6cxve6cxvA1A:123-360,A:380-403
P14902DB18267HEM6cxve6cxvB1B:123-360,B:380-402
P14902DB18267HEM6dpqe6dpqA1A:123-360,A:380-401
P14902DB18267HEM6dpre6dprA2A:123-360,A:380-401
P14902DB18267HEM6e35e6e35A2A:123-360,A:380-401
P14902DB18267HEM6e35e6e35B1B:123-360,B:380-402
P14902DB18267HEM6e40e6e40A2A:122-360,A:380-402
P14902DB18267HEM6e40e6e40B2B:122-360,B:380-401
P14902DB18267HEM6e40e6e40C2C:122-360,C:380-401
P14902DB18267HEM6e40e6e40D1D:123-360,D:380-401
P14902DB18267HEM6e41e6e41A1A:123-360,A:380-402
P14902DB18267HEM6e41e6e41B1B:123-360,B:380-401
P14902DB18267HEM6e41e6e41C2C:123-360,C:380-401
P14902DB18267HEM6e41e6e41D2D:123-360,D:380-401
P14902DB18267HEM6e42e6e42A2A:122-360,A:381-402
P14902DB18267HEM6e42e6e42B2B:122-360,B:380-401
P14902DB18267HEM6e42e6e42C1C:122-360,C:380-401
P14902DB18267HEM6e42e6e42D2D:123-360,D:380-401
P14902DB18267HEM6e44e6e44A1A:122-360,A:381-401
P14902DB18267HEM6e44e6e44B1B:123-360,B:380-401
P14902DB18267HEM6e44e6e44C2C:122-360,C:380-402
P14902DB18267HEM6e44e6e44D1D:122-360,D:380-401
P14902DB18267HEM6e45e6e45A1A:122-360,A:381-401
P14902DB18267HEM6e45e6e45B1B:123-360,B:380-401
P14902DB18267HEM6e45e6e45C1C:122-360,C:380-402
P14902DB18267HEM6e45e6e45D1D:122-360,D:380-401
P14902DB18267HEM6e46e6e46A2A:123-360,A:380-402
P14902DB18267HEM6e46e6e46B1B:123-360,B:380-401
P14902DB18267HEM6e46e6e46C1C:123-360,C:380-401
P14902DB18267HEM6e46e6e46D2D:123-360,D:380-401
P14902DB18267HEM6f0ae6f0aA1A:123-360,A:380-403
P14902DB18267HEM6f0ae6f0aC2C:123-360,C:380-402
P14902DB18267HEM6kofe6kofA2A:122-360,A:380-400
P14902DB18267HEM6kofe6kofB1B:122-360,B:380-403
P14902DB18267HEM6kpse6kpsA1A:122-360,A:380-400
P14902DB18267HEM6kpse6kpsB1B:122-360,B:380-403
P14902DB18267HEM6kw7e6kw7A1A:122-360,A:380-400
P14902DB18267HEM6kw7e6kw7B2B:122-360,B:380-403
P14902DB18267HEM6mq6e6mq6A1A:123-360,A:380-402
P14902DB18267HEM6o3ie6o3iA2A:123-360,A:380-401
P14902DB18267HEM6o3ie6o3iB1B:122-360,B:380-401
P14902DB18267HEM6pu7e6pu7A2A:123-360,A:380-401
P14902DB18267HEM6pu7e6pu7B2B:122-361,B:381-402
P14902DB18267HEM6pz1e6pz1A1A:123-360,A:380-401
P14902DB18267HEM6pz1e6pz1B1B:123-360,B:380-401
P14902DB18267HEM6r63e6r63A1A:122-361,A:382-402
P14902DB18267HEM6r63e6r63B1B:123-360,B:380-402
P14902DB18267HEM6ubpe6ubpA1A:123-360,A:380-403
P14902DB18267HEM6ubpe6ubpB1B:123-360,B:380-401
P14902DB18267HEM7a62e7a62A1A:123-360,A:380-401
P14902DB18267HEM7a62e7a62B1B:123-360,B:380-403
P14902DB18267HEM7a62e7a62C2C:123-360,C:380-403
P14902DB18267HEM7a62e7a62D1D:123-360,D:380-401
P14902DB18267HEM7ah4e7ah4A1A:122-360,A:381-403
P14902DB18267HEM7ah4e7ah4B2B:123-360,B:380-401
P14902DB18267HEM7ah5e7ah5A2A:122-361,A:381-402
P14902DB18267HEM7ah5e7ah5B1B:122-360,B:380-401
P14902DB18267HEM7ah6e7ah6A1A:122-361,A:381-403
P14902DB18267HEM7ah6e7ah6B2B:122-360,B:381-401
P14902DB18267HEM7e0oe7e0oA1A:123-360,A:380-400
P14902DB18267HEM7e0oe7e0oB1B:123-360,B:380-400
P14902DB18267HEM7e0pe7e0pA1A:123-360,A:380-401
P14902DB18267HEM7e0pe7e0pB1B:123-360,B:380-401
P14902DB18267HEM7e0qe7e0qA1A:123-360,A:382-401
P14902DB18267HEM7e0qe7e0qB1B:123-360,B:382-401
P14902DB18267HEM7e0se7e0sA1A:123-356,A:376-402
P14902DB18267HEM7e0se7e0sB1B:123-356,B:376-402
P14902DB18267HEM7e0te7e0tA1A:123-356,A:376-400
P14902DB18267HEM7e0te7e0tB1B:123-360,B:380-400
P14902DB18267HEM7e0ue7e0uA1A:123-356,A:376-402
P14902DB18267HEM7e0ue7e0uB1B:123-356,B:376-402
P14902DB18267HEM7m7de7m7dA1A:123-361,A:383-402
P14902DB18267HEM7m7de7m7dB1B:123-356,B:376-401
P14902DB18267HEM7ngee7ngeA1A:123-356,A:376-400
P14902DB18267HEM7ngee7ngeB1B:123-356,B:376-401
P14902DB18267HEM7ngee7ngeC1C:123-356,C:376-403
P14902DB18267HEM7ngee7ngeD1D:123-361,D:382-400
P14902DB18267HEM7p0ne7p0nA1A:123-356,A:376-401
P14902DB18267HEM7p0ne7p0nB1B:123-356,B:376-403
P14902DB18267HEM7p0ne7p0nC1C:123-356,C:376-403
P14902DB18267HEM7p0ne7p0nD1D:123-356,D:376-403
P14902DB18267HEM7p0re7p0rA1A:123-356,A:376-402
P14902DB18267HEM7p0re7p0rB1B:123-356,B:376-402
P14902DB18267HEM7p0re7p0rC1C:123-356,C:376-403
P14902DB18267HEM7p0re7p0rD1D:123-356,D:376-403
P14902DB18267HEM7yxte7yxtA2A:123-360,A:380-403
P14902DB18267HEM7yxte7yxtB1B:123-360,B:380-402
P14902DB18267HEM7yxte7yxtC1C:123-360,C:380-402
P14902DB18267HEM7yxte7yxtD2D:123-360,D:380-403
P14902DB18267HEM7z2le7z2lA1A:122-361,A:381-402
P14902DB18267HEM7z2le7z2lB2B:123-360,B:380-402
P14902DB18267HEM7z2le7z2lC2C:123-360,C:380-402
P14902DB18267HEM7z2le7z2lD1D:123-360,D:380-403
P14902DB18267HEM7zv3e7zv3A1A:122-360,A:380-403
P14902DB18267HEM7zv3e7zv3B1B:123-360,B:380-401