DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Serine/threonine-protein kinase B-raf
Ligand Name
N-{3-[2-(2-hydroxyethoxy)-6-(morpholin-4-yl)pyridin-4-yl]-4-methylphenyl}-2-(trifluoromethyl)pyridine-4-carboxamide
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
UEPXBTCUIIGYCY-UHFFFAOYSA-N
SMILES
Cc1ccc(cc1c2cc(nc(c2)OCCO)N3CCOCC3)NC(=O)c4ccnc(c4)C(F)(F)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 6N0P
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse6n0pA1e6n0pB1
ECOD domains from experimental PDB structures interacting with ligand DB18865
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P15056DB18865K816n0pe6n0pA1A:449-721
P15056DB18865K816n0pe6n0pB1B:449-721
P15056DB18865K818f7pe8f7pA1A:449-721
P15056DB18865K818f7pe8f7pB1B:448-721