DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Serine/threonine-protein kinase B-raf
Ligand Name
5-[(4-amino-1-ethyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)ethynyl]-N-(4-chlorophenyl)-6-methylisoquinolin-1-amine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
AZFFXPMHTGBCGM-UHFFFAOYSA-N
SMILES
CCn1c2c(c(n1)C#Cc3c(ccc4c3ccnc4Nc5ccc(cc5)Cl)C)c(ncn2)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 6NSQ
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Color Legend
Unassigned regionsLigand / hetero atomse6nsqA1e6nsqB1
ECOD domains from experimental PDB structures interacting with ligand KZP
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P15056n/aKZP6nsqe6nsqA1A:448-722
P15056n/aKZP6nsqe6nsqB1B:447-701