DrugDomain logoDrugDomain

Dabrafenib

P15056 — Serine/threonine-protein kinase B-raf

← Back

Attributes

UniProt ID
P15056
Protein Name
Serine/threonine-protein kinase B-raf
Ligand Name
Dabrafenib
DrugBank ID
DB08912
PDB Ligand Accession
P06
ChEMBL ID
CHEMBL2028663
PubChem ID
44462760
InChIKey
BFSMGDJOXZAERB-UHFFFAOYSA-N
SMILES
CC(C)(C)c1nc(c(s1)c2ccnc(n2)N)c3cccc(c3F)NS(=O)(=O)c4c(cccc4F)F
Drug Action
inhibitor
Affinity Metrics
ic50:0.4 nM
ec50:0.7 nM