DrugDomain logoDrugDomain

Attributes

UniProt ID
P15056
Protein Name
Serine/threonine-protein kinase B-raf
Ligand Name
Dabrafenib
DrugBank ID
DB08912
PDB Ligand Accession
P06
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
BFSMGDJOXZAERB-UHFFFAOYSA-N
SMILES
CC(C)(C)c1nc(c(s1)c2ccnc(n2)N)c3cccc(c3F)NS(=O)(=O)c4c(cccc4F)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 4XV2
Open File
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse4xv2A1e4xv2B1
ECOD domains from experimental PDB structures interacting with ligand DB08912
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P15056DB08912P064xv2e4xv2A1A:449-720
P15056DB08912P064xv2e4xv2B1B:448-720
P15056DB08912P065cswe5cswA1A:449-595,A:615-721
P15056DB08912P065cswe5cswB1B:447-721
P15056DB08912P065hiee5hieA1A:449-722
P15056DB08912P065hiee5hieB1B:449-722
P15056DB08912P065hiee5hieC1C:449-722
P15056DB08912P065hiee5hieD1D:449-722
P15056DB08912P066v2ue6v2uA1A:449-721
P15056DB08912P066v2ue6v2uB1B:449-720