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Attributes

UniProt ID
P16184
Protein Name
Dihydrofolate reductase
Ligand Name
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DrugBank ID
DB02338
PDB Ligand Accession
NDP
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ACFIXJIJDZMPPO-NNYOXOHSSA-N
SMILES
c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=CCC(=C5)C(=O)N)O)O)O)OP(=O)(O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Mol*
Structure: 1DAJ
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Color Legend
Unassigned regionsLigand / hetero atomse1dajA1
ECOD domains from experimental PDB structures interacting with ligand DB02338
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P16184DB02338NDP1daje1dajA1A:1-206
P16184DB02338NDP1dyre1dyrA1A:2-206
P16184DB02338NDP1klke1klkA1A:4-206
P16184DB02338NDP1vj3e1vj3A1A:2-206
P16184DB02338NDP2fzhe2fzhA1A:1-206
P16184DB02338NDP2fzie2fziA1A:1-206
P16184DB02338NDP3nz6e3nz6X1X:1-206
P16184DB02338NDP3nz9e3nz9X1X:1-206
P16184DB02338NDP3nzae3nzaX1X:1-206
P16184DB02338NDP3nzbe3nzbX1X:1-206
P16184DB02338NDP3td8e3td8A2A:5-206
P16184DB02338NDP4g8ze4g8zX1X:3-206
P16184DB02338NDP4ixee4ixeD1D:1-206
P16184DB02338NDP4ixfe4ixfX1X:1-206
P16184DB02338NDP4ixge4ixgX1X:1-206
P16184DB02338NDP4qjze4qjzD1D:1-206