Attributes
UniProt ID
Protein Name
Vascular endothelial growth factor receptor 1
Ligand Name
[6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl]methyl dihydrogen phosphate
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
GKDRMWXFWHEQQT-UHFFFAOYSA-N
SMILES
CC1(C(=O)N(c2c(ccc(n2)Nc3c(cnc(n3)Nc4cc(c(c(c4)OC)OC)OC)F)O1)COP(=O)(O)O)C
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: P17948_F1
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomsnD1nD2nD3nD4nD5nD8
ECOD domains from AlphaFold model interacting with ligand DB12010
| UniProt | DrugBank | PDB Ligand | ECOD Domain | Range Definition |
|---|---|---|---|---|
| P17948 | DB12010 | 2RC | nD1 | 26-135 |
| P17948 | DB12010 | 2RC | nD2 | 136-225 |
| P17948 | DB12010 | 2RC | nD3 | 226-330 |
| P17948 | DB12010 | 2RC | nD4 | 331-425 |
| P17948 | DB12010 | 2RC | nD5 | 426-555 |
| P17948 | DB12010 | 2RC | nD8 | 801-950, 981-1180, 801-950, 981-1180, 801-950, 981-1180, 801-950, 981-1180, 801-950, 981-1180, 801-950, 981-1180, 801-950, 981-1180, 801-950, 981-1180, 801-950, 981-1180, 801-950, 981-1180, 801-950, 981-1180, 801-950, 981-1180, 801-950, 981-1180, 801-950, 981-1180, 801-950, 981-1180, 801-950, 981-1180, 801-950,981-1180 |