FE3-S4 CLUSTER

P18188 — Periplasmic hydrogenase large subunit

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand F3S

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand F3S

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P18188	n/a	1frf	F3S	S	266	e1frfL2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	1yqw	F3S	A	266	e1yqwQ8	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	1yqw	F3S	B	266	e1yqwR8	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	1yqw	F3S	C	266	e1yqwS8	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	1yrq	F3S	A	266	e1yrqH8	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	1yrq	F3S	B	266	e1yrqI8	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	1yrq	F3S	C	266	e1yrqJ8	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	1yrq	F3S	D	266	e1yrqK8	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	1yrq	F3S	F	266	e1yrqM8	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	1yrq	F3S	G	266	e1yrqN8	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	3cur	F3S	A	266	e3curH2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	3cur	F3S	B	266	e3curI2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	3cur	F3S	C	266	e3curJ2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	3cus	F3S	A	266	e3cusQ2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	3cus	F3S	B	266	e3cusR2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	3cus	F3S	C	266	e3cusS2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	3h3x	F3S	A	266	e3h3xQ2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	3h3x	F3S	B	266	e3h3xR2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	3h3x	F3S	C	266	e3h3xS2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	4ucx	F3S	A	1266	e4ucxQ2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	4ucx	F3S	B	1266	e4ucxR2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	4ucx	F3S	C	1266	e4ucxS4	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	4uew	F3S	A	1266	e4uewQ1	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	4uew	F3S	B	1266	e4uewR4	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	4uew	F3S	C	1266	e4uewS1	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	4upe	F3S	A	1266	e4upeQ4	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	4upe	F3S	B	1266	e4upeR1	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	4upe	F3S	C	1266	e4upeS1	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	4uqp	F3S	A	1266	e4uqpQ2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
P18188	n/a	4uqp	F3S	B	1266	e4uqpR1	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases