methyl 4-ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxylate

P18507 — Gamma-aminobutyric acid receptor subunit gamma-2 receptor subunit gamma-2

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand R63

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
P18507	None	R63	002388936	11.12.1	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
P18507	None	R63	002388943	11.12.1	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD

Show other predicted domains (13)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
6D6U	e6d6uE1	5057.1.1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
6HUG	e6hugC2	11.12.1	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
6HUG	e6hugC1	5057.1.1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
6HUJ	e6hujC2	11.12.1	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
6HUJ	e6hujC1	5057.1.1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
6HUK	e6hukC2	11.12.1	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
6HUK	e6hukC1	5057.1.1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
6HUO	e6huoC2	11.12.1	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
6HUO	e6huoC1	5057.1.1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
6HUP	e6hupC2	11.12.1	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
6HUP	e6hupC1	5057.1.1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
6I53	e6i53C1	11.12.1	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
6I53	e6i53C2	5057.1.1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb

ECOD domains from experimental PDB structures interacting with ligand R63

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P18507	n/a	8dd3	R63	D	701	e8dd3E2	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD