Attributes
UniProt ID
Protein Name
Glutamate receptor 2
Ligand Name
3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
VLSMHEGGTFMBBZ-OOZYFLPDSA-N
SMILES
CC(=C)C1CNC(C1CC(=O)O)C(=O)O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 1FTK
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Color Legend
Unassigned regionsLigand / hetero atomse1ftkA1e1ftkA2
ECOD domains from experimental PDB structures interacting with ligand KAI
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P19491 | n/a | KAI | 1ftk | e1ftkA1 | A:121-234 |
| P19491 | n/a | KAI | 1ftk | e1ftkA2 | A:16-120,A:235-277 |
| P19491 | n/a | KAI | 1fw0 | e1fw0A1 | A:4-108,A:219-261 |
| P19491 | n/a | KAI | 1fw0 | e1fw0A2 | A:109-218 |
| P19491 | n/a | KAI | 1gr2 | e1gr2A1 | A:16-120,A:235-277 |
| P19491 | n/a | KAI | 1gr2 | e1gr2A2 | A:121-234 |
| P19491 | n/a | KAI | 1lbb | e1lbbA1 | A:109-218 |
| P19491 | n/a | KAI | 1lbb | e1lbbA2 | A:4-108,A:219-261 |
| P19491 | n/a | KAI | 1p1n | e1p1nA1 | A:109-218 |
| P19491 | n/a | KAI | 1p1n | e1p1nA2 | A:4-108,A:219-261 |
| P19491 | n/a | KAI | 1xhy | e1xhyA1 | A:1-105,A:216-259 |
| P19491 | n/a | KAI | 1xhy | e1xhyA2 | A:106-215 |
| P19491 | n/a | KAI | 2anj | e2anjA1 | A:109-218 |
| P19491 | n/a | KAI | 2anj | e2anjA2 | A:1-108,A:219-262 |
| P19491 | n/a | KAI | 3t9h | e3t9hB1 | B:4-108,B:219-261 |
| P19491 | n/a | KAI | 3t9h | e3t9hB2 | B:109-218 |
| P19491 | n/a | KAI | 3t9h | e3t9hD1 | D:4-108,D:219-261 |
| P19491 | n/a | KAI | 3t9h | e3t9hD2 | D:109-218 |
| P19491 | n/a | KAI | 3t9h | e3t9hF1 | F:4-108,F:219-261 |
| P19491 | n/a | KAI | 3t9h | e3t9hF2 | F:109-218 |
| P19491 | n/a | KAI | 4u1o | e4u1oA1 | A:109-218 |
| P19491 | n/a | KAI | 4u1o | e4u1oA2 | A:2-108,A:219-263 |
| P19491 | n/a | KAI | 4u1w | e4u1wA1 | A:498-506,A:631-730 |
| P19491 | n/a | KAI | 4u1w | e4u1wA4 | A:392-497,A:731-784 |
| P19491 | n/a | KAI | 4u1w | e4u1wB3 | B:392-497,B:731-784 |
| P19491 | n/a | KAI | 4u1w | e4u1wB5 | B:498-506,B:631-730 |
| P19491 | n/a | KAI | 4u1w | e4u1wC1 | C:392-497,C:731-774 |
| P19491 | n/a | KAI | 4u1w | e4u1wC5 | C:498-506,C:631-730 |
| P19491 | n/a | KAI | 4u1w | e4u1wD4 | D:392-497,D:731-784 |
| P19491 | n/a | KAI | 4u1w | e4u1wD5 | D:498-506,D:631-730 |
| P19491 | n/a | KAI | 4u1x | e4u1xA3 | A:392-497,A:731-776 |
| P19491 | n/a | KAI | 4u1x | e4u1xA4 | A:498-506,A:631-730 |
| P19491 | n/a | KAI | 4u1x | e4u1xB2 | B:498-506,B:631-730 |
| P19491 | n/a | KAI | 4u1x | e4u1xB5 | B:392-497,B:731-776 |
| P19491 | n/a | KAI | 4u1x | e4u1xC2 | C:498-506,C:631-730 |
| P19491 | n/a | KAI | 4u1x | e4u1xC4 | C:392-497,C:731-784 |
| P19491 | n/a | KAI | 4u1x | e4u1xD1 | D:392-497,D:731-784 |
| P19491 | n/a | KAI | 4u1x | e4u1xD5 | D:498-506,D:631-730 |
| P19491 | n/a | KAI | 4u1z | e4u1zA1 | A:109-218 |
| P19491 | n/a | KAI | 4u1z | e4u1zA2 | A:2-108,A:219-263 |
| P19491 | n/a | KAI | 4u2q | e4u2qA1 | A:498-506,A:631-730 |
| P19491 | n/a | KAI | 4u2q | e4u2qA4 | A:392-497,A:731-773 |
| P19491 | n/a | KAI | 4u2q | e4u2qB3 | B:498-506,B:631-730 |
| P19491 | n/a | KAI | 4u2q | e4u2qB5 | B:392-497,B:731-784 |
| P19491 | n/a | KAI | 4u2q | e4u2qC3 | C:392-497,C:731-784 |
| P19491 | n/a | KAI | 4u2q | e4u2qC5 | C:498-506,C:631-730 |
| P19491 | n/a | KAI | 4u2q | e4u2qD1 | D:392-497,D:731-784 |
| P19491 | n/a | KAI | 4u2q | e4u2qD5 | D:498-506,D:631-730 |
| P19491 | n/a | KAI | 4u5b | e4u5bA1 | A:383-497,A:731-789 |
| P19491 | n/a | KAI | 4u5b | e4u5bA5 | A:498-505,A:632-730 |
| P19491 | n/a | KAI | 4u5b | e4u5bB1 | B:498-505,B:632-730 |
| P19491 | n/a | KAI | 4u5b | e4u5bB3 | B:384-497,B:731-789 |
| P19491 | n/a | KAI | 4u5b | e4u5bC1 | C:382-497,C:731-789 |
| P19491 | n/a | KAI | 4u5b | e4u5bC5 | C:498-505,C:632-730 |
| P19491 | n/a | KAI | 4u5b | e4u5bD1 | D:498-505,D:632-730 |
| P19491 | n/a | KAI | 4u5b | e4u5bD5 | D:382-497,D:731-789 |
| P19491 | n/a | KAI | 4u5d | e4u5dA2 | A:383-497,A:731-789 |
| P19491 | n/a | KAI | 4u5d | e4u5dA5 | A:498-505,A:632-730 |
| P19491 | n/a | KAI | 4u5d | e4u5dB1 | B:384-497,B:731-789 |
| P19491 | n/a | KAI | 4u5d | e4u5dB3 | B:498-505,B:632-730 |
| P19491 | n/a | KAI | 4u5d | e4u5dC3 | C:382-497,C:731-789 |
| P19491 | n/a | KAI | 4u5d | e4u5dC4 | C:498-505,C:632-730 |
| P19491 | n/a | KAI | 4u5d | e4u5dD1 | D:498-505,D:632-730 |
| P19491 | n/a | KAI | 4u5d | e4u5dD3 | D:382-497,D:731-789 |
| P19491 | n/a | KAI | 4u5e | e4u5eA3 | A:498-505,A:632-730 |
| P19491 | n/a | KAI | 4u5e | e4u5eA4 | A:383-497,A:731-789 |
| P19491 | n/a | KAI | 4u5e | e4u5eB4 | B:384-497,B:731-789 |
| P19491 | n/a | KAI | 4u5e | e4u5eB5 | B:498-505,B:632-730 |
| P19491 | n/a | KAI | 4u5e | e4u5eC1 | C:498-505,C:632-730 |
| P19491 | n/a | KAI | 4u5e | e4u5eC4 | C:382-497,C:731-789 |
| P19491 | n/a | KAI | 4u5e | e4u5eD2 | D:498-505,D:632-730 |
| P19491 | n/a | KAI | 4u5e | e4u5eD3 | D:382-497,D:731-789 |
| P19491 | n/a | KAI | 4u5f | e4u5fA2 | A:383-497,A:731-789 |
| P19491 | n/a | KAI | 4u5f | e4u5fA4 | A:498-505,A:632-730 |
| P19491 | n/a | KAI | 4u5f | e4u5fB3 | B:384-497,B:731-789 |
| P19491 | n/a | KAI | 4u5f | e4u5fB4 | B:498-505,B:632-730 |
| P19491 | n/a | KAI | 4u5f | e4u5fC3 | C:498-505,C:632-730 |
| P19491 | n/a | KAI | 4u5f | e4u5fC5 | C:382-497,C:731-789 |
| P19491 | n/a | KAI | 4u5f | e4u5fD2 | D:382-497,D:731-789 |
| P19491 | n/a | KAI | 4u5f | e4u5fD4 | D:498-505,D:632-730 |