Attributes
UniProt ID
Protein Name
ATP-dependent translocase ABCB1
Ligand Name
(4~{S},11~{S},18~{S})-4,11-dimethyl-18-(sulfanylmethyl)-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ZWMLZIGVMMBHAX-CIUDSAMLSA-N
SMILES
CC1c2nc(cs2)C(=O)NC(c3nc(cs3)C(=O)NC(c4nc(cs4)C(=O)N1)CS)C
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 7ZK5
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Color Legend
Unassigned regionsLigand / hetero atomse7zk5A1e7zk5A2e7zk5A3e7zk5A4
ECOD domains from experimental PDB structures interacting with ligand JIZ
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P21447 | n/a | JIZ | 7zk5 | e7zk5A2 | A:688-1015 |
| P21447 | n/a | JIZ | 7zk5 | e7zk5A4 | A:34-372 |
| P21447 | n/a | JIZ | 7zk6 | e7zk6A1 | A:34-372 |
| P21447 | n/a | JIZ | 7zk6 | e7zk6A2 | A:688-1015 |
| P21447 | n/a | JIZ | 7zk8 | e7zk8A1 | A:34-372 |
| P21447 | n/a | JIZ | 7zk8 | e7zk8A4 | A:683-1015 |
| P21447 | n/a | JIZ | 7zk9 | e7zk9A1 | A:689-1015 |
| P21447 | n/a | JIZ | 7zk9 | e7zk9A3 | A:32-372 |
| P21447 | n/a | JIZ | 7zka | e7zkaA2 | A:34-372 |
| P21447 | n/a | JIZ | 7zka | e7zkaA4 | A:688-1015 |
| P21447 | n/a | JIZ | 7zkb | e7zkbA1 | A:32-372 |
| P21447 | n/a | JIZ | 7zkb | e7zkbA4 | A:689-1015 |