Attributes
UniProt ID
Protein Name
Pyruvate dehydrogenase E1 component subunit alpha
Ligand Name
THIAMINE DIPHOSPHATE
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
AYEKOFBPNLCAJY-UHFFFAOYSA-O
SMILES
Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCOP(=O)(O)OP(=O)(O)O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 1W85
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Color Legend
Unassigned regionsLigand / hetero atomse1w85A1e1w85B1e1w85B2e1w85C1e1w85D1e1w85D2e1w85E1e1w85F1e1w85F2e1w85G1e1w85H1e1w85H2e1w85I1e1w85J1
ECOD domains from experimental PDB structures interacting with ligand TPP
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P21873 | n/a | TPP | 1w85 | e1w85A1 | A:11-366 |
| P21873 | n/a | TPP | 1w85 | e1w85C1 | C:11-366 |
| P21873 | n/a | TPP | 1w85 | e1w85E1 | E:11-366 |
| P21873 | n/a | TPP | 1w85 | e1w85G1 | G:11-366 |
| P21873 | n/a | TPP | 1w88 | e1w88A1 | A:11-366 |
| P21873 | n/a | TPP | 1w88 | e1w88C1 | C:11-366 |
| P21873 | n/a | TPP | 1w88 | e1w88E1 | E:11-265,E:292-366 |
| P21873 | n/a | TPP | 1w88 | e1w88G1 | G:11-265,G:292-366 |