DrugDomain logoDrugDomain

Attributes

UniProt ID
P22288
Protein Name
GTP cyclohydrolase 1
Ligand Name
PHENYLALANINE
DrugBank ID
DB00120
PDB Ligand Accession
PHE
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
COLNVLDHVKWLRT-QMMMGPOBSA-N
SMILES
c1ccc(cc1)CC(C(=O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 1IS7
Open File
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse1is7A1e1is7B1e1is7C1e1is7D1e1is7E1e1is7F1e1is7G1e1is7H1e1is7I1e1is7J1e1is7K1e1is7L1e1is7M1e1is7N1e1is7O1e1is7P1e1is7Q1e1is7R1e1is7S1e1is7T1
ECOD domains from experimental PDB structures interacting with ligand DB00120
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P22288DB00120PHE1is7e1is7A1A:56-240
P22288DB00120PHE1is7e1is7B1B:56-240
P22288DB00120PHE1is7e1is7C1C:56-240
P22288DB00120PHE1is7e1is7D1D:56-240
P22288DB00120PHE1is7e1is7E1E:56-240
P22288DB00120PHE1is7e1is7F1F:56-240
P22288DB00120PHE1is7e1is7H1H:56-240
P22288DB00120PHE1is7e1is7I1I:56-240
P22288DB00120PHE1is7e1is7J1J:56-240
P22288DB00120PHE1is8e1is8A1A:56-240
P22288DB00120PHE1is8e1is8B1B:56-240
P22288DB00120PHE1is8e1is8D1D:56-240
P22288DB00120PHE1is8e1is8E1E:56-240
P22288DB00120PHE1is8e1is8F1F:56-240
P22288DB00120PHE1is8e1is8G1G:56-240
P22288DB00120PHE1is8e1is8H1H:56-240
P22288DB00120PHE1is8e1is8I1I:56-240
P22288DB00120PHE1is8e1is8J1J:56-240