DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Fibroblast growth factor receptor 4
Ligand Name
N-(4-{[3-(3,5-dimethoxyphenyl)-7-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl}phenyl)propanamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
DKHGWJNITASDGF-UHFFFAOYSA-N
SMILES
CCC(=O)Nc1ccc(cc1)CN2c3c(cnc(n3)Nc4ccc(cc4)N5CCN(CC5)C)CN(C2=O)c6cc(cc(c6)OC)OC
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 4QQ5
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse4qq5A1
ECOD domains from experimental PDB structures interacting with ligand 37O
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P22455n/a37O4qq5e4qq5A1A:447-755
P22455n/a37O4qqce4qqcA1A:443-750