1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one
P22607 — Fibroblast growth factor receptor 3
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB15149
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| P22607 | DB15149 | TZ0 | nD2 | 11.1.1 | Immunoglobulin-like beta-sandwich | Immunoglobulin-related | Immunoglobulin/Fibronectin type III/E set domains/PapD-like | I-set |
| P22607 | DB15149 | TZ0 | nD3 | 11.1.1 | Immunoglobulin-like beta-sandwich | Immunoglobulin-related | Immunoglobulin/Fibronectin type III/E set domains/PapD-like | Ig_3 |
| P22607 | DB15149 | TZ0 | nD4 | 206.1.1 | Protein kinase/SAICAR synthase/ATP-grasp | Protein kinase/SAICAR synthase/ATP-grasp | Protein kinase | PK_Tyr_Ser-Thr |
Show other predicted domains (5)
| PDB ID | Domain Name | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|
| 1RY7 | e1ry7B1 | 11.1.1 | Immunoglobulin-like beta-sandwich | Immunoglobulin-related | Immunoglobulin/Fibronectin type III/E set domains/PapD-like | Cadherin |
| e1ry7B2 | 11.1.1 | Immunoglobulin-like beta-sandwich | Immunoglobulin-related | Immunoglobulin/Fibronectin type III/E set domains/PapD-like | Cadherin | |
| 2LZL | e2lzlA1 | 3774.1.1 | Fibroblast growth factor receptor 3 transmembrane domain | Fibroblast growth factor receptor 3 transmembrane domain | Fibroblast growth factor receptor 3 transmembrane domain | FGFR3_TM |
| e2lzlB1 | 3774.1.1 | Fibroblast growth factor receptor 3 transmembrane domain | Fibroblast growth factor receptor 3 transmembrane domain | Fibroblast growth factor receptor 3 transmembrane domain | FGFR3_TM | |
| 4K33 | e4k33A1 | 206.1.1 | Protein kinase/SAICAR synthase/ATP-grasp | Protein kinase/SAICAR synthase/ATP-grasp | Protein kinase | Pkinase |
ECOD domains from experimental PDB structures interacting with ligand DB15149
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| No experimental ECOD data found | ||||||||||