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Attributes

UniProt ID
P22906
Protein Name
Dihydrofolate reductase
Ligand Name
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DrugBank ID
DB02338
PDB Ligand Accession
NDP
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ACFIXJIJDZMPPO-NNYOXOHSSA-N
SMILES
c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=CCC(=C5)C(=O)N)O)O)O)OP(=O)(O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Mol*
Structure: 1AI9
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Color Legend
Unassigned regionsLigand / hetero atomse1ai9A1e1ai9B1
ECOD domains from experimental PDB structures interacting with ligand DB02338
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P22906DB02338NDP1ai9e1ai9A1A:1-192
P22906DB02338NDP1ai9e1ai9B1B:1-192
P22906DB02338NDP1aoee1aoeA1A:1-192
P22906DB02338NDP1aoee1aoeB1B:1-192
P22906DB02338NDP1ia1e1ia1A1A:1-192
P22906DB02338NDP1ia1e1ia1B1B:1-192
P22906DB02338NDP1ia2e1ia2A1A:1-192
P22906DB02338NDP1ia2e1ia2B1B:1-192
P22906DB02338NDP1ia3e1ia3A1A:1-192
P22906DB02338NDP1ia3e1ia3B1B:1-192
P22906DB02338NDP1ia4e1ia4A1A:1-192
P22906DB02338NDP1ia4e1ia4B1B:1-192
P22906DB02338NDP1m78e1m78A1A:1-192
P22906DB02338NDP1m78e1m78B1B:1-192
P22906DB02338NDP1m79e1m79A1A:1-192
P22906DB02338NDP1m79e1m79B1B:1-192
P22906DB02338NDP1m7ae1m7aA1A:1-192
P22906DB02338NDP1m7ae1m7aB1B:1-192
P22906DB02338NDP4hoee4hoeA1A:1-192
P22906DB02338NDP4hoee4hoeB1B:1-192
P22906DB02338NDP4hofe4hofA1A:1-192
P22906DB02338NDP4hofe4hofB1B:1-192