DrugDomain logoDrugDomain

2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE

P23254 — Transketolase 1

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand THD

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand THD

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P23254n/a1gpuTHDA1682e1gpuA2Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Transket_pyr
P23254n/a1gpuTHDA1682e1gpuA3Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Transketolase_N
P23254n/a1gpuTHDA1682e1gpuB2Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Transket_pyr
P23254n/a1gpuTHDB1682e1gpuA2Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Transket_pyr
P23254n/a1gpuTHDB1682e1gpuA3Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Transketolase_N
P23254n/a1gpuTHDB1682e1gpuB3Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Transketolase_N